Related Links
- Sudin Bhattacharya, Ph.D.
- Frank Boellmann, Ph.D.
- Jerry Campbell, Jr., Ph.D.
- Guilherme Garcia , Ph.D.
- Naresh Kumar, Ph.D.
- Dianxin Liu, M.D., Ph.D.
- Kambiz Nazridoust, Ph.D.
- Einav Shnaidman, PH.D.
- Haibo Wang, M.D., Ph.D.
- Xiao-Juan Wang, M.D., Ph.D.
- Miyoung Yoon, Ph.D.
Education and Outreach
Haibo Wang, M.D., Ph.D.
Division of Biological Sciences
Education
M.D., medicine, China Medical University, Shenyang, People's Republic of China, 1995.
Master's degree, pathophysiology and pathology, China Medical University, Shenyang, People's Republic of China, 1998.
Ph.D., pathophysiology and pathology, China Medical University, Shenyang, People's Republic of China, 2004.
Postdoctoral training, Division of Biological Sciences, CIIT Centers for Health Research, Research Triangle Park, North Carolina, 2004-present.
Research
Obesity is now at epidemic proportions and is a risk factor for several debilitating illnesses such as type II diabetes, hypertension, and cardiovascular disease. Brown adipose tissue, a thermogenic organ, is present in most mammals and is responsible for cold-induced, nonshivering thermogenesis, which is triggered by the activation of the sympathetic nervous system (SNS). One of the target genes activated by SNS response is the uncoupling protein 1 (UCP1) gene. Under the direction of Dr. Sheila Collins, I am studying the transcription factors involved in UCP1 gene expression. This work could provide insight into energy metabolism and clues that may lead to therapeutic approaches in treating diseases related to energy metabolism.
Selected Publications
Haibo Wang, Yuan Zhang, Einav Yehuda-Shnaidman, Alexander V. Medvedev,
Naresh Kumar, Kiefer W. Daniel, Jacques Robidoux, Michael P. Czech,
David J. Mangelsdorf, Sheila Collins: LXRα is a Transcriptional Repressor of the Uncoupling Protein-1
Gene and the Brown Fat Phenotype, Molecular and Cellular Biology (in press)