Publications
Selected Publications
Journal articles
Zhang Q., Bhattacharya S., Andersen M.E., and Conolly R.B. (2010). Computational Systems Biology and Dose Response Modeling in Relation to New Directions in Toxicity Testing. Journal of Toxicology and Environmental Health Part B. 13(2): 253-276.
Bhattacharya S., Conolly R.B., Kaminski N.E., Thomas R.S., Andersen M.E., and Zhang Q. (2010). A Bistable Switch Underlying B-Cell Differentiation and Its Disruption by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Toxicological Sciences. 115(1), 51–65.
Zhang Q., Bhattacharya S., Crawford R.B., Kline D.E.,Thomas R.S., Conolly R.B., Kaminski N.E., and Andersen M.E. (2010). Stochastic Modeling of B Cell Terminal Differentiation and Its Repression by Dioxin. BMC Systems Biology. 4:40.
Zhang Q., Pi J., Woods C.G., and Andersen M.E. (2010). A Systems Biology Perspective on Nrf2-mediated Antioxidant Response. Toxicology and Applied Pharmacology. 244(1): 84-97.
Zhang Q., Pi J., Woods C.G., and Andersen M.E. (2009). Phase I to II Cross-Induction of Xenobiotic Metabolizing Enzymes: a Feedforward Control Mechanism for Potential Hormetic Responses. Toxicology and Applied Pharmacology. 237(3): 345-356.
Zhang Q., Pi J., Woods C.G., Jarabek A.M., Clewell H.J. III, and Andersen M.E. (2008). Hormesis and Adaptive Cellular Control Systems. Dose-Response.6(2):196-208.
Li L., Heber S., Andersen M.E., and Zhang Q. (2007). Non-Monotonic Dose Response Relationship in Steroid Hormone Receptor-mediated Gene Expression. Journal of Molecular Endocrinology. 38(5): 569–585.
Zhang Q. and Andersen M.E. (2007). Dose Response Relationship in Anti-Stress Gene Regulatory Networks. PLoS Comput Biol. 3(3): e24.
Zhang Q., Andersen M.E., and Conolly R.B. (2006). Binary Gene Induction and Protein Expression in Individual Cells. Theor Biol Med Model. 3(1): 18.
Book chapters
Zhang Q., Bhattacharya S., Woods C.G., and Andersen M.E.(2010). Ultrasensitive Response Motifs in Biochemical Networks, in Quantitative Modeling in Toxicology, Krishnan K. and Andersen M.E. (ed), John Wiley & Sons, Hoboken, New Jersey.
Bhattacharya S., Zhang Q., and Andersen M.E.(2010). Bistable Signalling Motifs and Cell Fate Decisions, in Quantitative Modeling in Toxicology, Krishnan K. and Andersen M.E. (ed), John Wiley & Sons, Hoboken, New Jersey.
Andersen M.E.,Zhang Q., and Bhattacharya S. (2010). Modeling Gene and Protein Expression - Nested Motifs in Cellular and Tissue Response Networks, in Quantitative Modeling in Toxicology, Krishnan K. and Andersen M.E. (ed), John Wiley & Sons, Hoboken, New Jersey.
Zhang Q., Tan Y.M., Bhattacharya S., and Andersen M.E. (2009). Computational Systems Biology Modeling of Dosimetry and Cellular Response Pathways, in Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools, Ekins S. and Xu J.J. (ed), John Wiley & Sons, Hoboken, New Jersey.
McDougal J.N., Zheng Y, Zhang Q., and Conolly R.B. (2006). Biologically Based Pharmacokinetic and Pharmacodynamic Models of the Skin, in Dermal Absorption Models in Toxicology and Pharmacology, Riviere J.E. (ed), Taylor and Francis, London, UK.