Center for Computational Biology and Bioinformatics
The Center uses modeling and high-content data to deepen our understanding of how chemicals interact with biological systems. The Center will combine expertise and tools from different disciplines to develop innovative strategies for using large-scale data (from toxicogenomics, high-throughput screens, and other sources) to solve problems related to chemical and drug safety.
Patrick D. McMullen, Ph.D., Director
Patrick McMullen, Ph.D., serves as Director of The Center for Computational Biology and Bioinformatics at The Hamner Institutes for Health Sciences, and is a Hamner Research Investigator. Dr. McMullen has 10 years of experience in developing computational biology models and using high-throughput data streams to extend our understanding of molecular biology. He uses data from gene expression microarray, ChIP-seq, and metabolomics experiments to capture the interactions between biological systems and potential toxicants. The goal of this work is to replace conventional in-life animal testing with a chemical safety assessment paradigm that focuses on informative cell-based assays and predictive computational models. Dr. McMullen received his Ph.D. in Chemical & Biological Engineering from Northwestern University.