Scientists & Research
2007 Research Publications
Asgharian, B., and Price, O.T. (2007). Deposition of Ultrafine (nano) Particles in the Human Lung, Inhalation Toxicology 19:1045-1052.
Kumar N, Robidoux J, Daniel KW, Guzman G, Floering LM, Collins S. Requirement of vimentin filament assembly for beta3-adrenergic receptor activation of ERK MAP kinase and lipolysis. J Biol Chem. 2007 Mar 23;282(12):9244-50. Epub 2007 Jan 24.
Belfiore, C. J., Yang, R. S. H., Chubb, L. S., Lohitnavy, M., Lohitnavy, O. S., and Andersen, M. E. (2007). Hepatic sequestration of chlordecone and hexafluoroacetone evaluated by pharmacokinetic modeling. Toxicology 234, 59-72.
Cruzan, G., Borghoff, S. J., de Peyster, A., Hard, G. C., McClain, M., McGregor, D. B., and Thomas, M.G. (2007). Methyl tertiary-butyl ether mode of action for cancer endpoints in rodents. Regul. Toxicol. Pharmacol. 47, 156-165.
Li, L., Andersen, M. E., Heber, S., and Zhang, Q. (2007). Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression J. Mol. Endocrinol. 38, 569-585.
Liu, H. Y., Collins, Q. F., Xiong, Y., Moukdar, F., Lupo Jr., E. G., Liu, Z., and Cao, W. (2007). Prolonged treatment of primary hepatocytes with oleate induces insulin resistance through p38 mitogen-activated protein kinase. J. Biol. Chem. 282(19):14205-14212.
Wong, B. A. (2007). Inhalation exposure systems: Design, methods and operation. Toxicol. Pathol. 35(1), 3-14.
Sochaski, M. A., McManus, B. M., Struve, M. F., Wallace, D. G., and Dorman, D. C. (2007). Inhibition and recovery of maternal and foetal cholinesterase enzymes following fenitrothion administration in CD rats. Xenobiotica 37, 19-29.
Thomas, R. S., O'Connell, T. M., Pluta, L., Wolfinger, R. D., Yang, L., and Page, T. P. (2007). A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. Toxicol. Sci. 96, 40-46.
Xiong, Y., Collins, Q. F., An, J., Lupo, E. G. Jr., Liu, H.-Y., Liu, D., Robidoux, J., Liu, Z., and Cao, W. (2007). p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis. J. Biol. Chem. 282, 4975-4982.
Zager, M. G., Schlosser, P. M., and Tran, H. T. (2007). A delayed nonlinear PBPK model for genistein dosimetry in rats. Bull. Math. Biol. 69, 93-117.
Zhang, Q. and Andersen, M. E. (2007). Dose response relationship in anti-stress gene regulatory networks. PLoS Comput. Biol. Mar 2; 3(3):e24.
Teeguarden, J.G., Dorman, D.C., Covington, T.R., Clewell, H.J., III, Nong, A., and Andersen, M.E. (2007). Pharmacokinetic modeling of manganese. III. Physiological approaches accounting for background and tracer kinetics. J. Toxicol. Environ. Health, 70(18):1515-1526.
Liao, K.H., Tan, Y.-M., Conolly, R.B., and Clewell, H.J. (2007). Bayesian estimation of pharmacokinetic and pharmacodynamic parameters in a mode-of-action based cancer risk assessment for chloroform. Risk Anal., 27(6):1535-1551.
Liao, K.H., Tan, Y.-M., and Clewell, H.J. (2007). Development of a screening approach to interpret human biomonitoring data on volatile organic compounds (VOCs). Risk Anal., 27(5):1223-1236.
Allen, B.A., Hack, C.E., and Clewell, H.J. (2007). Use of Markov chain Monte Carlo analysis with a physiologically based pharmacokinetic model of methylmercury to estimate exposures in U.S. women of childbearing age. Risk Anal. 27(4):947-959.
Tan, Y.-M., Liao, K.H., and Clewell, H.J. (2007). Reverse dosimetry: Interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling. J. of Exposure Science and Environmental Epidemiology, 17:591–603.
Clewell, H.J., Thomas, R.S., Gentry, P.R., Crump, K.S., Kenyon, E.M., El-Masri, H.A., Yager, J.W. (2007). Research toward the development of a biologically based dose response assessment for inorganic arsenic carcinogenicity: A progress report. Toxicol. Appl. Pharmacol. 222:388–398.
Bahadori, T., Phillips, R.D., Money, C.D., Quackenboss, J.J., Clewell, H.J., Bus, J.S., Robison, S.H., Humphris, C.J., Parekh, A.A., Osborn, K., Kauffman, R.M. (2007). Making sense of human biomonitoring data: Findings and recommendations of a workshop. J Expo Sci Environ Epidemiol. (4):308-313.
Thomas, R.S., Allen, B.C., Nong, A., Yang, L., Bermudez, E., Clewell, H.J. 3rd, and Andersen, M.E. (2007). A Method to Integrate Benchmark Dose Estimates with Genomic Data to Assess the Functional Effects of Chemical Exposure. Toxicol Sci. 98(1):240-248
Pi J, Bai Y, Zhang Q, Floering LM, Wong V, Daniel K, Reece JM, Deeney JT, Corkey BE, Collins S. Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes. (2007); 56:1783-1791.
Pi J, Bai Y, Reece JM, William J, Liu D, Freeman ML, Fahl WE, Shugar D, Liu J, Qu W, Collins S, Waalkes MP. Molecular mechanism of Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2. Free Radic Biol Med. (2007); 42:1797-806.
Qu CF, Liu HY, Pi J, Liu Z, Quon MJ, Cao W. Epigallocatechin-3-3 gallate (EGCG), a green tea polyphenol, suppresses hepatic gluconeogenesis through 5’-AMP-activated protein kinase. J Biol Chem. (2007); 282:30143-9.
Qu W, Ke H, Pi J, Broderick D, French JE, Webber MM, Waalkes MP. Acquisition of apoptotic resistance in cadmium-transformed human prostate epithelial cells: Bcl-2 overexpression blocks the activation of JNK signal transduction pathway. Environ Health Perspect. (2007);115:1094-100.
Cui R, Iso H, Pi J, Kumagai Y, Yamagishi K, Tanigawa T, Shimamoto T. Metabolic syndrome and urinary cGMP excretion in general population. Atherosclerosis. (2007); 190:423-428.
Wikstrom JD, Katzman SM, Mohamed H, Twig G, Graf SA, Heart E Molina AJA, Corkey BE, de Vargas LM, Danial NN, Collins S, Shirihai O (2007) b-cell mitochondria exhibit membrane potential heterogeneity that can be altered bv stimulatory or toxic fuel levels. Diabetes 56: 2569-2578.
Pi, J., Bai, Y., Zhang, Q., Floering, L. M., Wong, V., Daniel, K., Reece, J. M., Deeney, J. T., Corkey, B. E., and Collins S. (2007). Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes. In press.
Pi, J., Bai, Y., Reece, J. M., William, J., Liu, D., Freeman, M. L., Fahl, W. E., Shugar, D., Liu, J., Qu, W., Collins, S., and Waalkes, M. P. (2007). Molecular mechanism of Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2. Free Radic. Biol. Med. 42, 1797-1806.
Collins, Q.F., Liu H.Y., Xiong Y., Quon, M., and W. Cao. Epigallocatechin gallate (EGCG) suppresses hepatic gluconeogenesis through AMP activated protein kinase (AMPK). J. Biol. Chem., (2007), 282:30143-49.
Liu, H. Y., Collins, Q. F., Xiong, Y., Moukdar, F., Lupo, E. G., Liu, Z., and Cao, W. (2007). Prolonged treatment of primary hepatocytes with oleate induces insulin resistance through p38 mitogen-activated protein kinase. J. Biol. Chem. 282, 14205-14212.
Xiong, Y., Collins, Q. F., An, J., Lupo, E., Liu, H. Y., Liu, D., Robidoux, J., Liu, Z., and Cao. W. (2007). p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis. J. Biol. Chem. 282, 4975-4982.