http://www.thehamner.org/news-events/entry/thomas-and-wetmore-to-present-at-icca-lri-and-ncats-workshop http://www.thehamner.org/news-events/entry/idss-scientists-to-highlight-drug-safety-conference-at-world-pharma-congres http://www.thehamner.org/news-events/entry/melvin-andersen-to-serve-on-organizing-committee-for-fda-workshop http://www.thehamner.org/news-events/entry/paul-watkins-to-speak-at-hepatology-360-conference http://www.thehamner.org/news-events/entry/russell-thomas-to-speak-at-ilsi-health-and-environmental-sciences-insti http://www.thehamner.org/news-events/entry/melvin-andersen-to-lead-course-at-karolinska-institutet http://www.thehamner.org/news-events/entry/brett-howell-to-present-poster-at-american-conference-on-pharmacometric http://www.thehamner.org/news-events/entry/melvin-andersen-to-co-chair-session-on-developing-microphysiological-sy http://www.thehamner.org/news-events/entry/paul-watkins-to-speak-at-medical-grand-rounds http://www.thehamner.org/news-events/entry/joe-trask-to-present-at-perkin-elmer-global-health-summit RESEARCH TRIANGLE PARK, NC – The Hamner Institutes for Health Sciences (www.thehamner.org) announces the release of DILIsym® v2A. DILIsym® is developed and released as part of the DILI-sim Initiative (www.dilisym.com), an effort to develop a mathematical, mechanistic model of drug-induced liver injury chaired by Dr. Paul B. Watkins. DILIsym® v2A was made available to all DILI-sim Initiative industry members as of April 10th, 2013. http://www.thehamner.org/news-events/entry/the-hamner-releases-dilisym-v2a http://www.thehamner.org/news-events/entry/melvin-andersen-to-present-at-us-endocrine-disruptor-screening-program http://www.thehamner.org/news-events/entry/the-hamner-exhibiting-at-bio-2013 http://www.thehamner.org/news-events/entry/russell-thomas-to-speak-at-croplife-america-spring-conference http://www.thehamner.org/news-events/entry/dr.-ed-lecluyse-to-speak-at-north-jersey-acs-dmdg-spring-symposium http://www.thehamner.org/news-events/entry/idss-scientists-to-present-at-issx-workshop Hamner and UNC researchers have demonstrated that using a mouse diversity panel may more accurately predict human safety risks over current nonclinical models. http://www.thehamner.org/news-events/entry/a-new-approach-to-better-predict-clinical-kidney-injury RESEARCH TRIANGLE PARK, NC, April 04, 2013 -- The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced that its scientists have been recognized with 12 awards from the Society of Toxicology (SOT), a professional organization committed to creating a safer and healthier world by advancing the science of toxicology, at the group's 52nd annual meeting held March 10-14 in San Antonio, Texas. The honors follow an impressive presence at the meeting that consisted of nearly 50 presentations by Hamner scientists. http://www.thehamner.org/news-events/entry/scientists-at-the-hamner-institutes-for-health-sciences-receive-12-awards-f http://www.thehamner.org/news-events/entry/hamner-awards-at-the-2013-society-of-toxicology-annual-meeting http://www.thehamner.org/news-events/entry/the-hamner-at-the-2013-society-of-toxicology-annual-meeting http://www.thehamner.org/news-events/entry/russell-thomas-to-speak-at-risk-sciences-international-uofottawa-semina http://www.thehamner.org/news-events/entry/lab-automation-sparks-creativity http://www.thehamner.org/news-events/entry/william-greenlee-to-sit-on-ced-biopharma-panel http://www.thehamner.org/news-events/entry/mispro-biotech-services-announces-partnership-with-the-hamner-news-clips RESEARCH TRIANGLE PARK, N.C. – February 26, 2013 – On the eve of the CED Life Science Conference 2013 (Feb. 27-28), Mispro Biotech Services, a leading provider of multi-user vivarium space and remote husbandry services, and The Hamner Institutes for Health Sciences, a nonprofit research organization focused on translational safety sciences, have announced their partnership in Research Triangle Park, NC. http://www.thehamner.org/news-events/entry/mispro-biotech-services-announces-partnership-with-the-hamner-institutes-fo http://www.thehamner.org/news-events/entry/russell-thomas-at-who-ipcs-workshop http://www.thehamner.org/news-events/entry/the-hamner-announces-partnership-with-qps-news-clips RESEARCH TRIANGLE PARK, N.C. – February 14, 2013 – The Hamner Institutes for Health Sciences, a nonprofit research organization focused on translational safety sciences, and QPS Holdings, LLC, a Newark, Delaware USA headquartered contract research organization (CRO), have announced the launch of QPS Hepatic Biosciences, a center of excellence for cell based research and services. Hepatic Biosciences is a new division within the QPS DMPK department and will specialize in hepatocyte research, drug metabolism, drug transporter sciences, and in vitro drug-drug interactions. The scientific discipline of this new operation at The Hamner Institutes is jointly led by Drs. Edward LeCluyse, Associate Investigator at The Hamner, and Caroline Lee, Director of Drug Metabolism and Transporter Sciences at QPS. Hepatic Biosciences has also assumed responsibility for all GLP-compliant quality assurance and bioanalysis in support of The Hamner. In addition to augmenting existing Hamner research programs, QPS will focus on new business development for both organizations. http://www.thehamner.org/news-events/entry/the-hamner-institutes-for-health-sciences-announces-partnership-with-qps-ho http://www.thehamner.org/news-events/entry/a-game-changer-in-toxicity-testing http://www.thehamner.org/news-events/entry/russell-thomas-to-speak-at-ucla-cein-workshop http://www.thehamner.org/news-events/entry/joe-trask-to-speak-at-society-of-laboratory-automation-and-screening-meetin http://www.thehamner.org/news-events/entry/joe-trask-to-present-at-chi-high-content-analysis-meeting http://www.thehamner.org/news-events/entry/qps-and-the-hamner-host-eric-solon-seminar http://www.thehamner.org/news-events/entry/hamner-institute-ceo-talks-importance-of-partnerships http://www.thehamner.org/news-events/entry/hamner-institutes-partners-with-brown-university-on-toxicity-testing RESEARCH TRIANGLE PARK, N.C. – The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced the establishment of a pre-competitive, multi-organization partnership designed to advance an integrated systems biology approach to toxicity testing research. The Hamner and Brown University will conduct the research. Partners sponsoring the research include Agilent Technologies Inc., Illumina, Dow Chemical, Dow Corning Corporation, ExxonMobil, Unilever and CropLife America member companies. The Long-Range Research Initiative (LRI) of the American Chemistry Council supported earlier stages of this research. http://www.thehamner.org/news-events/entry/the-hamner-institutes-for-health-sciences-announces-integrated-biology-init http://www.thehamner.org/news-events/entry/hamner-announces-integrated-biology-initiative http://www.thehamner.org/news-events/entry/agilent-illumina-sponsor-alliance-established-for-toxicity-testing-using-in http://www.thehamner.org/news-events/entry/thomas-to-present-at-society-of-toxicology-of-canada-annual-symposium http://www.thehamner.org/news-events/entry/top-10-innovations-2012 http://www.thehamner.org/news-events/entry/paul-watkins-to-speak-at-reactive-metabolites-conference http://www.thehamner.org/news-events/entry/harrill-and-thomas-to-speak-at-hesi-drug-safety-workshop Raleigh-Durham-Chapel Hill, NC -- The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced that Dr. Jingbo Pi, associate investigator, is lead author of a scientific report showing that nuclear factor E2-related factor 2 (Nrf2), a key oxidative stress signaling protein, is involved in the growth of fat stores in the body. This finding may have important consequences for the treatment of obesity and diabetes. The paper will appear in an upcoming edition of Diabetes, the official journal of the American Diabetes Association. http://www.thehamner.org/news-events/entry/the-hamner-institutes-for-health-sciences-jingbo-pi-publishes-report-on http://www.thehamner.org/news-events/entry/new-master-plan-unveiled-for-research-triangle-park http://www.thehamner.org/news-events/entry/hamner-idss-co-sponsoring-best-practices-workshop-on-liver-safety-assessmen http://www.thehamner.org/news-events/entry/paul-watkins-to-lead-course-at-aasld-liver-meeting http://www.thehamner.org/news-events/entry/the-hamner-receives-funding-from-croplife-america-members http://www.thehamner.org/news-events/entry/russell-thomas-to-be-keynote-speaker-at-south-central-regional-sot-chap http://www.thehamner.org/news-events/entry/russell-thomas-to-speak-at-international-society-of-exposure-science-me http://www.thehamner.org/news-events/entry/virtual-liver-may-be-cure-for-drug-failures-in-clinical-trials http://www.thehamner.org/news-events/entry/hamner-scientists-to-speak-at-futuretox Research Triangle Park, NC, October 18, 2012 -- The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced that a team of researchers within the Institute for Chemical Safety Sciences has received the 2012 Simcyp Academic IVIVE Award for Most Informative Scientific Report at the Simcyp Consortium Meeting held Sept 17 in Sheffield, England. Dr. Barbara A. Wetmore, a senior research investigator and lead author of “Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment,” accepted the award and presented the report findings to the consortium members. Researchers at The Hamner Institutes, in collaboration with scientists at the Environmental Protection Agency, measured the ability of chemicals to be cleared by the liver and bound to proteins in the blood, two key determinants of how long a chemical will reside in the body following exposure. These data were then used to estimate the daily dose a person would need to be exposed to in order for the chemical to achieve internal concentrations similar to those that elicited biological activities in the high-throughput assays. The work was published earlier this year in the journal Toxicological Sciences (http://www.ncbi.nlm.nih.gov/pubmed/21948869). http://www.thehamner.org/news-events/entry/the-hamner-institutes-for-health-sciences-wins-simcyp-academic-ivive-award http://www.thehamner.org/news-events/entry/hamner-institutes-win-simcyp-academic-research-award http://www.thehamner.org/news-events/entry/merrie-mosedale-receives-award-at-nc-society-of-toxicology-fall-meeting http://www.thehamner.org/news-events/entry/russell-thomas-to-give-seminar-at-health-canada http://www.thehamner.org/news-events/entry/hamner-institutes-to-sponsor-environmental-health-summit http://www.thehamner.org/news-events/entry/hamner-institutes-announces-award-for-associate-director RESEARCH TRIANGLE PARK, N.C. – The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced that Dr. Melvin Andersen, associate director of the Institute for Chemical Safety Sciences and Charles E. Hamner Jr. Distinguished Fellow, has received the Alternatives Research & Development Foundation’s 2012 William and Eleanor Cave Award for achievements in advancing alternatives to the use of animals in research and testing (http://www.ardf-online.org/caveAward-2012.pdf). Andersen accepted the award at the American Society For Cellular and Computational Toxicology (ASCCT) meeting on Sept. 21 in Bethesda, Md., where he presented a plenary lecture titled “Computational Cellular Pathway Modeling: Combining Key In Vitro and In Silico Tools to Enhance Modern Safety Assessment.” http://www.thehamner.org/news-events/entry/the-hamner-institutes-mel-andersen-honored-with-the-william-and-eleanor http://www.thehamner.org/news-events/entry/melvin-andersen-to-speak-at-ebi-industry-workshop http://www.thehamner.org/news-events/entry/melvin-andersen-to-present-plenary-lecture-at-ascct-meeting http://www.thehamner.org/news-events/entry/bin-sun-received-award-at-2012-ems-annual-meeting http://www.thehamner.org/news-events/entry/harvey-clewell-invited-to-speak-at-fda http://www.thehamner.org/news-events/entry/greenlee-stays-on-as-chief-executive-at-hamner RESEARCH TRIANGLE PARK, N.C. – The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced that Dr. William Greenlee has been reappointed as president and CEO of the nonprofit research organization for a five-year term. Greenlee is the visionary leader behind the re-positioning of The Hamner as a multi-disciplinary, integrated, translational research center that features globally recognized platforms in chemical and drug safety. He has led The Hamner and its predecessor, CIIT, as president and CEO since 1999. http://www.thehamner.org/news-events/entry/the-hamner-institutes-reappoints-william-greenlee-as-president-and-ceo http://www.thehamner.org/news-events/entry/brett-howell-to-speak-at-american-chemical-society-national-meeting http://www.thehamner.org/news-events/entry/russell-thomas-to-give-ascct-webinar http://www.thehamner.org/news-events/entry/overtaking-the-dili-model-t RESEARCH TRIANGLE PARK, N.C. – Jul 24, 2012 – The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced that it will offer a one week course from Monday, Sept. 24 through Friday, Sept. 28 that covers the principles of pharmacokinetic modeling and the applications of the technique in risk assessment, drug development in vitro to in vivo extrapolation (IVIVE) and the estimation of exposures from human biomonitoring data. The course features comprehensive lectures and extensive hands-on computer modeling practice, led by Drs. Harvey Clewell, Melvin Andersen and faculty from The Hamner’s Center for Human Health Assessment. Attendees may claim up to six hours per day for American Board of Industrial Hygiene (ABIH) CM credit. http://www.thehamner.org/news-events/entry/hamner-institutes-to-offer-course-on-the-principles-of-pbpk-modeling http://www.thehamner.org/news-events/entry/tbj-reveals-triangles-most-influential-business-leaders http://www.thehamner.org/news-events/entry/russell-thomas-to-present-at-society-of-toxicologic-pathology-symposium http://www.thehamner.org/news-events/entry/agilent-to-accelerate-development-in-toxicology-testing-with-funding-from-n http://www.thehamner.org/news-events/entry/hamner-institute-examining-impact-of-drugs-on-liver-health RESEARCH TRIANGLE PARK, N.C. – The Hamner Institutes for Health Sciences (The Hamner) has announced the formation of the DILI-sim Initiative, a pre-competitive partnership between The Hamner and a diverse set of stakeholders to develop a computational model that will predict whether new drug candidates will cause drug-induced liver injury (DILI) in patients. The goals of the Initiative are to improve patient safety, reduce the need for animal testing, and reduce the costs and time necessary to develop new drugs. It is the intent of the DILI-sim Initiative to make the model, in the form of DILIsymTM software, broadly available so that it may be used by the pharmaceutical industry, the U.S. Food and Drug Administration (FDA), and other entities in academia, government and industry. http://www.thehamner.org/news-events/entry/the-hamner-institutes-for-health-sciences-announces-formation-of-dili-sim-i http://www.thehamner.org/news-events/entry/russell-thomas-to-speak-at-eurotox-2012 http://www.thehamner.org/news-events/entry/melvin-andersen-to-serve-on-us-steering-committee-for-ebtc-europe http://www.thehamner.org/news-events/entry/ed-lecluyse-to-speak-at-new-england-drug-metabolism-discussion-group http://www.thehamner.org/news-events/entry/russell-thomas-to-present-at-icca-lri-and-uk-hpa-workshop http://www.thehamner.org/news-events/entry/melvin-andersen-to-present-at-axlr8-3-workshop http://www.thehamner.org/news-events/entry/jingbo-pi-to-attend-72nd-ada-scientific-sessions http://www.thehamner.org/news-events/entry/idss-to-speak-at-2012-world-pharma-congress http://www.thehamner.org/news-events/entry/tt21c-what-does-it-take-to-become-a-new-paradigm http://www.thehamner.org/news-events/entry/charles-hamner-epic-games-rule-at-full-steam-awards http://www.thehamner.org/news-events/entry/russell-thomas-to-present-at-ara-dose-response-workshop http://www.thehamner.org/news-events/entry/agilent-partners-developing-toxicology-testing-models-with-6m-nih-grant http://www.thehamner.org/news-events/entry/russell-thomas-to-give-seminar-at-johns-hopkins http://www.thehamner.org/news-events/entry/hamner-to-lead-systems-biology-and-dose-response-course-in-italy http://www.thehamner.org/news-events/entry/rtp-seeks-to-be-more-inviting-for-smaller-companies-quick-innovation http://www.thehamner.org/news-events/entry/melvin-andersen-to-speak-at-brown-university http://www.thehamner.org/news-events/entry/charles-hamner-at-nanotech-commercialization-conference http://www.thehamner.org/news-events/entry/paul-watkins-cder-seminar-available-for-online-viewing RESEARCH TRIANGLE PARK, N.C. – The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced that four scientists have been recognized with awards from the Society of Toxicology, a professional organization committed to creating a safer and healthier world by advancing the science of toxicology at their 51st Annual Meeting that was held March 11-15 in San Francisco. http://www.thehamner.org/news-events/entry/2012-sot-awards http://www.thehamner.org/news-events/entry/pending-information-shift-with-new-toxicity-testing-a-deal-with-the-devil http://www.thehamner.org/news-events/entry/syngenta-principal-scientist-speaks-at-personal-care-products-council-confe http://www.thehamner.org/news-events/entry/melvin-andersen-to-be-panelist-at-croplife-america-conference http://www.thehamner.org/news-events/entry/acetaminophen-poisoning-new-knowledge-and-new-treatments http://www.thehamner.org/news-events/entry/hamner-biotech-growth-to-last-until-2035 http://www.thehamner.org/news-events/entry/melvin-andersen-to-give-lecture-at-university-of-ottawa RESEARCH TRIANGLE PARK, N.C. – The Hamner Institutes for Health Sciences (http://www.thehamner.org) has announced that its scientists will be presenting over 40 talks and posters and leading workshops on topics covering a variety of current trends and issues in the field of toxicology at the Society of Toxicology’s 51st Annual Meeting & ToxExpoTM Sunday, March 11 through Thursday, March 15 at the Moscone Convention Center, located at 747 Howard Street in San Francisco, CA. http://www.thehamner.org/news-events/entry/society-of-toxicology-annual-meeting-2012 http://www.thehamner.org/news-events/entry/drs-watkins-and-lecluyse-at-fda-c-path-phrma-liver-meeting http://www.thehamner.org/news-events/entry/drug-data-reveal-sneaky-side-effects