News & Events


Forthcoming Seminars

The NC Biomedical Innovation Network Symposium on February 26th has been cancelled and will be rescheduled at a later date.

Recently Held Seminars

Alex Tropsha, Ph.D.
Chair, Division of Medicinal Chemistry and Natural Products, University of North Carolina, School of Pharmacy
Are in vitro data useful for predicting chemical toxicity?
Thursday, October 29, 2009

Don Rose, Ph.D.
Vice President, Metabolon Inc., Research Triangle Park, NC
The application of metabolomics to drug action and safety
Thursday, November 12, 2009

Shawn Burgess, Ph.D.
Advanced Imaging Research Center and Department of Pharmacology
Graduate School of Biomedical Sciences University of Texas Southwestern Medical Center
Title pending
Thursday, November 19, 2009

Lee Graves, Ph.D.
Department of Pharmacology University of North Carolina, School of Medicine
Title pending
Thursday, December 3, 2009

William K. Kaufmann, Ph.D.
Department of Pathology and Laboratory Medicine, University of North Carolina,
School of Medicine
Systems biology of environmental cancer
Thursday, October 1, 2009
10:00 am

Daniel Gatti
Postdoc Candidate in Environmental Sciences & Engineering with a Certificate in Bioinformatics and Computational Biology, Gillings School of Global Public Health, UNC at Chapel Hill
Genome-Wide Association Mapping in Inbred Mice
Tuesday, October 20, 2009
2:00 pm

Les Recio, Ph.D., DABT
Division Director, Genetic Toxicology, ILS, Research Triangle Park, NC
Quantitative Measures of Genotoxicity and Mutagenicity to Examine Dose-Response of Genotoxic Exposures
Wednesday, August 26, 2009

O. Joseph Trask, Jr.
Head of Cellular Imaging Technologies, Center for Drug Discovery,
Duke University Medical Center, Durham, NC
High Content Imaging Approaches to Study Neurodegeneration in Primary Cells & Tissue
Monday, August 31, 2009

Paul Carmichael, Ph.D.
Science Leader: Prevention of Cancer, Unilever - Safety and Environmental Assurance Centre
Colworth Science Park, Sharnbrook, Bedfordshire, UK
Unilever and the Cancer Risk Assessment of Cosmetic Ingredients - the In Vitro Challenge
Monday, August 10, 2009

Dr. Richard Brennan
Director of Toxicology, GeneGo Inc.
In Silico Differentiation of Reactive Metabolite Generation and Cardiotoxicity Profiles for the Anti-psychotic Drugs Clozapine and Olanzapine
Wednesday, May 13, 2009

Lishan Su, Ph.D.
Professor of Microbiology & Immunology, Lineberger Cancer Center, UNC at Chapel Hill
Modeling Therapeutic Applications of Human Stem Cells in Mice: Blood and Liver
Thursday, April 2, 2009

William Wetsel, Ph.D.
Associate Research Professor Director, Mouse Behavioral and Neuroendocrine Analysis Core Facility Psychiatry and Behavioral Sciences Duke University Medical Center, Durham, NC Phenotyping Mice with Attitudes
Friday, April 3, 2009

Alison Harrill, Ph.D.
Postdoctoral Fellow, The Hamner – UNC Center for Drug Safety Sciences
The Road to Personalized Medicine: Systems Biology Approaches to Understand
and Predict Toxicity

Friday, April 3, 2009

Dr. Tim Wiltshire
Associate Professor, Department of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, UNC at Chapel Hill
Genetic Variation in Mice: Modeling Disease, Pharmacogenetics, and Basic Biology
Wednesday, March 11

David Threadgill, Ph.D.
Chair, Department of Genetics, North Carolina State University
Epidermal Growth Factor Receptor: An Evolving Story of Gene X Environment Interactions
in Cancer, Obesity and Heart Disease

Friday, February 13, 2009

David Moore, Ph.D.
Department of Cell Biology, Baylor College of Medicine, Houston, TX      
Lipotropic nuclear receptors - Best for diabetes?
Friday, March 6, 2009

Kim Brouwer, Pharm.D., Ph.D.
George H. Cocolas Distinguished Professor and Chair,
Pharmacotherapy & Experimental Therapeutics,
UNC Eshelman School of Pharmacy 
Hepatic Transporters and Hepatotoxicity
Thursday, February 5

Cynthia Sollod, Ph.D.
Manager, Science and Technology Development Program North Carolina Biotechnology Center Funding Opportunities through the North Carolina Biotechnology Center
Tuesday, January 27

Mathew Pletcher, Ph.D.
Senior Principal Scientist, Investigative Toxicology, Pfizer Global Research and Development
Inbred Mouse Genomics: Using a Mouse Model to Better Understand Human Phenotypic Diversity
Thursday, January 15, 2009

Jefferson Chan M.D., Ph.D.
Associate Professor, Department of Laboratory Medicine and Pathology University of California Irvine School of Medicine
Molecular and Genetic Analysis of Nrf1 Transcription Factor in Stress Response
Friday, January 16, 2009

Gregg L. Semenza, M.D., Ph.D.
Director, Vascular Program, Institute for Cell Engineering
C. Michael Armstrong Professor, Departments of Pediatrics, Medicine, Oncology,
Radiation Oncology and the McKusick-Nathans Institute of Genetic Medicine
The Johns Hopkins University School of Medicine
Baltimore, MD
Targeting HIF-1 for Therapy of Cancer and Ischemic Cardiovascular Disease
Wednesday, November 12, 2008

Yohannes Tesfaigzi, Ph.D.
Senior Scientist & Director COPD Program
Lovelace Respiratory Research Institute Albuquerque, NM
Resolution of Epithelial Cell Hyperplasia
Wednesday, November 26, 2008

Pere Puigserver, PhD
Assistant Professor, Department of Cell Biology
Dana Farber Cancer Institute
Boston, MA
New Components in Insulin Signaling and Control of Glucose Homeostasis
Friday, December 5, 2008

Michael Marletta, PhD
Aldo DeBenedictis Professor of Chemistry
Professor of Biochemistry and Molecular Biology, University of California, Berkeley
Sensing Gases Selectively: NO Signaling in an Aerobic Environment
Friday, November 7, 2008

Bryan Roth MD, PhD
Michael Hooker Professor
Director NIMH Psychoactive Drug Screening Program, UNC Chapel Hill Medical School
Mining the receptorome: a highly efficient approach for therapeutic target discovery
and validation

Friday, September 19, 2008

John S. Rhee, MD, MPH, FACS
Associate Professor, Medical College of Wisconsin
Anatomic nasal obstruction: A model of integrative outcomes research
Friday, October 17

Scott Alper, Ph.D.
Staff Scientist, National Heart, Lung, and Blood Institute National Institutes of Health
c/o National Institute of Environmental Health Sciences
Research Triangle Park, NC
Identification of Novel Innate Immunity Genes and Pathways Using Comparative Genomics
June 24, 200

Allison Elizabeth Ashley-Koch, Ph.D.
Associate Professor, Center for Human Genetics
Department of Medicine at Duke University Medical Center
Unraveling the complex genetics of psychiatric disease
June 27, 2008

Peter Yau, Ph.D.
Director, Protein Sciences Facility
University of Illinois at Urbana-Champaign
Applying Proteomics in Biomedical Research
April 25, 2008

Andrew A. Butler, Ph.D.
Associate Professor, Pennington Biomedical Research Center
Louisiana State University System
Baton Rouge, Louisiana
A Novel Endocrine Mechanism Involved in Lipid Homeostasis
May 23, 2008

Reen Wu, Ph.D.
Professor, Internal Medicine and VM Anatomy, Physiology and Cell Biology
Center for Comparative Respiratory Biology and Medicine
University of California at Davis
Davis, CA
Regulation of Airway Mucin Gene Expression: Signaling and Epigenetic Mechanisms
Friday, March 28, 2008

Dr. Peter Di
Assistant Professor, Center for Lung Regeneration
Director, Inhalation Exposure Facility
Department of Environmental and Occupational Health
University of Pittsburgh
Environmental tobacco smoke exposure and health effect: What do we learn
from mouse models?

Thursday, February 28th

Paul B. Watkins, M.D.
Verne S. Avidness Professor of Medicine
Director, Translation al and Clinical Sciences Institute
University of North Carolina at Chapel Hill
Chapel Hill, NC
Why Good Drugs are Sometimes Bad for the Liver
Friday, February 22

Peter Koopman, Ph.D.
ARC Federation Fellow
Professor of Developmental Biology
Institute for Molecular Bioscience
The University of Queensland
Somatic and Germ Cell Sex Determination in Mice
Thursday, February 14, 2008

Timothy Galitski, Ph.D.
Associate Professor
Institute for Systems Biology
Seattle, WA
Prediction of Phenotype and Gene Expression for Combinations of Mutations
Friday, February 8, 2008

David J. Mangelsdorf, Ph.D.
Professor and Chair, Department of Pharmacology
Investigator, Howard Hughes Medical Institute
Doris and Bryan Wildenthal Distinguished Chair in Medical Science
University of Texas Southwestern Medical Center
Dallas, TX
Nuclear Receptor Regulation of Metabolism: From Feast to Famine
Tuesday, February 5, 2008

Benoit Nemery, M.D., Ph.D.
Professor of Toxicology & Occupational Medicine
Chair of Department of Public Health
The Catholic University of Leuven
Leuven, Belgium
A Mouse Model of Chemical-Induced Occupational Asthma
Wednesday, January 16th, 2008

Christopher B. Newgard, Ph.D.
Director, Sarah W. Stedman Nutrition and Metabolism Center
Duke University Medical Center
Durham, NC
Comprehensive Metabolic Analysis Tools for Understanding of Disease Mechanisms
Friday, December 7, 2007

Silvia Corvera, M.D.
University of Massachusetts Medical School
Worcester, MA
Control of Adipose Tissue Function Through Angiogenesis
Friday, October 19, 2007

Urmila P. Kodavanti, Ph.D.
Experimental Toxicology Division
National Health and Environmental Effects Research Laboratory
U.S. Environmental Protection Agency
Research Triangle Park, NC
Genetic Cardiovascular Dieases and Air Pollution Susceptibility
Friday, September 21, 2007

Harry Roels, Ph.D.
Professor Emeritus
Unit of Industrial Toxicology and Occupational Medicine
Catholic University of Louvain
Brussels, Belgium
Health Risk Assessment of Neurotoxic Exposure to Manganese in Workers Exposed to Inhalable Dust or Welding Fume
Monday, September 17, 2007

James Inglese, Ph.D.
Deputy Director
NIH Chemical Genomics Center
Rockville, Maryland
Evaluating Chemical Libraries Using Quantitative High Throughput Screening for Molecular Probe Discovery and Toxicological Profiling
Friday, September 7, 2007

Orian Shirihai, M.D., Ph.D.
Assistant Professor
Department of Pharmacology
Tufts University School of Medicine
Boston, Massachusetts
Social Life of Mitochondria within the Cell: Dynamic Clubs, Connected Networks and Depolarized Singles
Friday, August 31, 2007

Michael P. Waalkes, Ph.D.
Laboratory of Comparative Carcinogenesis
Head, Inorganic Carcinogenesis Section
Research Triangle Park, North Carolina
Mechanisms in Arsenic Carcinogenesis: From Humans to Mice to Molecules and Back Again Friday, August 3, 2007

Keith M. Erikson, Ph.D.
Assistant Professor
Department of Nutrition
The University of North Carolina Greensboro
Greensboro, North Carolina
Manganese Neurotoxicity: Nutritional and Neurochemical Aspects
Friday, July 27, 2007

Julianne M. Hall, Ph.D.
Research Scientist
Department of Pharmacology and Cancer Biology
Duke University Medical Center
Durham, North Carolina
Evaluating PPARgamma as a Therapeutic Target in Human Breast Cancer
Thursday, July 12, 2007

Wolfgang Liedtke, M.D., Ph.D.
Assistant Professor and Head of Laboratory
Klingenstein Fellow
Attending Physician, Duke Pain Clinics
Duke University Medical Center
Center for Translational Neuroscience
Durham, North Carolina
Physiological and Pathophysiological Role of trpv4
Friday, June 22, 2007

Mark R. Wiesner, Ph.D.
James L. Meriam Professor of Civil & Environmental Engineering
Pratt School of Engineering
Nicholas School of the Environment and Earth Sciences
Duke University
Durham, North Carolina
Elements of Risk Assessment for Manufactured Nanomaterials: The Fullerene Example
Wednesday, June 13, 2007

Steven R. Kleeberger, Ph.D.
Chief, Laboratory of Respiratory Biology
National Institute of Environmental Health Sciences
National Institutes of Health
Research Triangle Park, North Carolina
Positional Cloning of Lung Injury Susceptibility Genes - from Mouse to Man
Friday, May 4, 2007

Vernon E. Steele, Ph.D., M.P.H.
Program Director
Chemoprevention Agent Development Research Group
Division of Cancer Prevention
National Cancer Institute
Bethesda, Maryland
Cancer Chemoprevention: An Applied Science Translatable to Clinical Practice
Wednesday, May 2, 2007

Atul J. Butte, M.D., Ph.D.
Assistant Professor
Stanford University School of Medicine
Director, Center for Pediatric Bioinformatics
Lucile Packard Children's Hospital
Stanford, California
Exploring Genomic Medicine Using Integrative Biology
Friday, April 13, 2007

Scott P. Kennedy, Ph.D.
Vice President
Development, Regulatory Strategy, and Centers of Emphasis Line
Pfizer Global Research and Development
Pfizer Inc.
Groton, CT
Foundation for Innovation: Pharma-Academic Partnerships
Friday, March 23, 2007

Tony K.T. Lam, Ph.D.
John Kitson McIvor Endowed Chair in Diabetes Research
Assistant Professor of Physiology and Medicine
Toronto General Hospital Research Institute
University Health Network and University of Toronto
Toronto, Ontario, Canada
CNS Nutrient Sensing Controls Liver Nutrient Production
Friday, March 23, 2007

Kevin J. Luebke, Ph.D.
Assistant Professor
Department of Internal Medicine
Division of Translational Research
University of Texas Southwestern Medical Center
Dallas, Texas
Remote Control of Cells with Light-Activated Epidermal Growth Factor
Friday, February 16, 2007

Arthur A. Levin, Ph.D., DABT
Vice President, Drug Development
Toxicology and Pharmacokinetics
ISIS Pharmacueticals
Carlsbad, California
Understanding the Pharmacokinetics and Pharmacodynamics of an Antisense Therapeutic:
From Bench to Bedside

Monday, January 29, 2007

Liangyou Rui, Ph.D.
Assistant Professor
Department of Molecular and Integrative Physiology
University of Michigan Medical School
Ann Arbor, Michigan
SH2B Regulation of Energy and Glucose Metabolism by Enhancing Leptin and Insulin Sensitivity
Friday, January 26, 2007

Micaela B. Reddy, Ph.D.
Research Scientist
Roche Palo Alto LLC
Palo Alto, California
Prospects for the Application of PBPK Modeling in Drug Development
Thursday, January 11, 2007